Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression.

Br J Cancer · 2011 · PMC3039790 · PMID 21102583

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0580

boldest claim

The sentences

highly significantP <10 −6actually significant

Bioinformatic screens for differential TACE mRNA expression using the Oncomine database ( www.oncomine.org ) confirmed the highly significant ( P <10 −6 ) increase in TACE transcript levels in HNSCC specimens ( Cromer et al , 2004 ).

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of borderline significanceP =0.058so close (0.05 < p ≤ 0.1)

There was also a correlation of borderline significance between high TIMP3 mRNA levels in tumour-associated stromal areas and a reduced overall survival of HNSCC patients analysed ( P =0.058, Figure 4B ).

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