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Improvements in population-based survival of patients presenting with metastatic rectal cancer in the south of the Netherlands, 1992-2008.

Clin Exp Metastasis · 2011 · PMC3040315 · PMID 21207120

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an increasing trendno p-value reported
Median survival of patients receiving chemotherapy also showed an increasing trend until 2000–2004 without any further improvement afterwards, although confidence limits overlapped throughout the whole study period.

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