A similar highly significant conservation in hPSD proteins was found in other pairs of compared species: human/chimp (LCA~6 my), human/macaque (LCA~30 my) and mouse/rat (LCA ~20 my) 5 showing the purifying selection (conservation) was not unique to the human lineage ( Supplementary Fig. 2c–e ).
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Characterization of the proteome, diseases and evolution of the human postsynaptic density.
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