We found that 18–26% (depending on the tissue) of loci classified as T-DMRs in either human or chimpanzee are shared between the two species ( Figure 3A , Table S2 ), a highly significant overlap compared to that expected by chance alone (hypergeometric distribution P values across all pairwise tissue comparisons <10 −16 ).
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A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues.
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