a small trendp<0.0001
For the KEGG 3+DB signalling pathways network betweenness centrality – a measure of the difference between the node with the highest betweenness centrality (the node on the most shortest paths) to all other nodes in the network – we did see a small trend towards pathway networks having lower betweenness centrality (p<0.0001 (WNT pathway) to p<0.837 (VEGF pathway).