Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study.

When added to a multivariable base model for LNN disease - which included the traditional prognostic factors of age, menopausal status, grade, and PGR - stratified by ESR1 and tumor size to meet the proportional hazards assumption, the association of DC-SCRIPT with MFS remained highly significant (HR 0.60; P < 0.001) (Table 2 ).

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