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Caenorhabditis elegans chromosome arms are anchored to the nuclear membrane via discontinuous association with LEM-2.

Genome Biol · 2010 · PMC3046480 · PMID 21176223

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a positive trendno p-value reported
Although there is a positive trend between chromosome size and the LEM-2 occupancy (that is, proportion of LEM-2 binding region per chromosome) for the autosomes, the second-largest chromosome is the X, which had the lowest LEM-2 occupancy.

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