Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans.

Diabetes · 2011 · PMC3046853 · PMID 21270237

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a nonsignificant trendno p-value reported

There was a nonsignificant trend for insulin concentrations to be slightly higher in IH and slightly lower in IH + PBA compared with SAL and PBA ( Fig. 1 B ).

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