Barely Significant
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Thermostability in endoglucanases is fold-specific.

BMC Struct Biol · 2011 · PMC3047435 · PMID 21291533

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highly significantno p-value reported
Comparison of intramolecular interactions showed that cation-π interactions are highly significant in imparting thermophilicity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.