Differences in the mannose oligomer specificities of the closely related lectins from Galanthus nivalis and Zea mays strongly determine their eventual anti-HIV activity.

Retrovirology · 2011 · PMC3048538 · PMID 21314946

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highly significantno p-value reported

Such unusual preference for deletion of high-mannose-type glycans is highly significant for these lectins since the glycan shield of the HIV-1 gp120 envelope, determined for gp120 expressed in Chinese hamster ovary (CHO) cells, exists of 11 high-mannose- or hybrid-type glycans and 13 complex-type glycans [ 28 ].

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