A new method for morphometric analysis of tissue distribution of mobile cells in relation to immobile tissue structures.

Results Distribution of CD56 + cells and of CXCR3 + cells in the decidua of first trimester pregnancy in relation to endothelium of vessels devoid of a layer of smooth vasculature For all widths of the neighborhood areas tested (from the smallest size of 0–10 μm up to a width of 0–50 μm around the vessel endothelium, in increments of 10 μm) a highly significant accumulation of CXCR3 + cells was found in the vicinity of endothelium of vessels which do not contain a muscular layer, as compared to the cell density in the residual decidua ( Figure 10a ; p<0.001 for all tested neighborhood widths).

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