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Increasing incidence and mortality of infective endocarditis: a population-based study through a record-linkage system.

BMC Infect Dis · 2011 · PMC3051911 · PMID 21345185

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an increasing trendno p-value reported
Discussion Our study demonstrates an increasing trend in incidence and mortality for IE in the Veneto Region over the last decade.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.