Barely Significant
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Accurate and fast simulation of channel noise in conductance-based model neurons by diffusion approximation.

PLoS Comput Biol · 2011 · PMC3053314 · PMID 21423712

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extremely significantno p-value reported
The impact of the first quantitative deterministic description of conductance gating [2] was extremely significant, as testified by its wide use up to today [3] .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.