Furthermore, the increase in S phase arrests in cells with a CAG-155 repeat was evident in the rad52Δ background and was highly significant compared to rad52Δ CAG-0 or CAG-70 (26% vs. 7–8%, Figure 4A ).
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Expanded CAG/CTG repeat DNA induces a checkpoint response that impacts cell proliferation in Saccharomyces cerevisiae.
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