In order to investigate whether a possible trend may be assumed in the comparisons of GIC and amalgam, the chronological results from 4 datasets concerning restorations (single- and multiple surface combined) after 1 year (DS 07), 2 years (DS 08), 3 years (DS 14) and 5 years (DS 01) were included in a cumulative meta-analysis [ 20 , 25 , 26 ].
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Absence of carious lesions at margins of glass-ionomer cement and amalgam restorations: An update of systematic review evidence.
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