Barely Significant
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Acute endotoxin-induced thymic atrophy is characterized by intrathymic inflammatory and wound healing responses.

PLoS One · 2011 · PMC3060875 · PMID 21437240

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highly significantno p-value reported
Pathway analysis identified the IL-17 signaling pathway as highly significant ( Figures 3 and S4 ), suggesting both intrathymic production of, and response to, pro-inflammatory cytokines and chemokines.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.