Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome.

Diabetes · 2011 · PMC3064099 · PMID 21346177

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highly significantno p-value reported

Uric acid induced a highly significant increase in MCP-1 mRNA in cells and protein concentration in the conditioned medium ( Fig. 2 A and B ) while the presence of MnTMPyP or apocynin in the medium completely prevented these effects ( Fig. 2 A and B ).

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