Acute toxicity of second generation HIV protease-inhibitors in combination with radiotherapy: a retrospective case series.

The difference between the two groups in number of AIDS-defining malignancies almost reached statistical significance (p = 0.06), but the remainder of the malignancies (HIV-associated and non-HIV-associated) are not differently distributed in the two groups (p = 0.9). 29 cases had documented pre-treatment CD4 counts; 4 were <50 (4 [24%] with PIs), 13 were <200 (9 [53%] with PIs, 4 [33%] without PIs), and 21 were <500 (10 [59%] with PIs; 11[92%] without PIs).

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