Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2.

Silence · 2011 · PMC3068080 · PMID 21401928

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of borderline significanceno p-value reported

There was only a small enrichment of borderline significance in the ORF of TGFBR2 , but after removal of sequences with a seed match to the TGFBR2 3' UTR, the signal became significant (see Additional File 1 Figure S4).

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