Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody.

This is the reason for the high signal background in the wound area seen in both animal groups, after injection of 111 In-control but also with 111 In-LIBS. However, the uptake signal caused by specific binding of 111 In-LIBS at the carotid artery thrombosis is still sufficient to obtain a highly significant signal.

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