Barely Significant
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The Toll-like receptor gene family is integrated into human DNA damage and p53 networks.

PLoS Genet · 2011 · PMC3069118 · PMID 21483755

Europe PMCDOI
1
hedged sentence
0.0001
closest p · 0.0× alpha
0.0001
boldest claim

The sentences

highly significantp<0.0001actually significant
As expected, induction of the p21 gene in the population was highly significant for all the treatments (p<0.0001).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.