Low CD4/CD8 T-cell ratio associated with inflammatory arthropathy in human T-cell leukemia virus type I Tax transgenic mice.

There was no statistically significant gender difference in the 2-year cumulative incidence of arthropathy; however, there was an apparent trend that male mice had a somewhat higher cumulative incidence than female mice ( Figure 1C , right; P = 0.082, one-tailed Fisher's exact test).

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