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Disease-related changes in the cerebrospinal fluid metabolome in amyotrophic lateral sclerosis detected by GC/TOFMS.

PLoS One · 2011 · PMC3070699 · PMID 21483737

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an overall trendno p-value reported
An overall trend was decreased levels of many CSF metabolites in ALS.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.