Post hoc comparisons demonstrated that mGlu5 KO mice were significantly more active than WT mice during the last 50 min of the test session. For entropy, there was a main effect of MPEP treatment that approached but did not reach significance ( F (1, 24) = 4.09; p < 0.06), and there was an interaction between treatment and gene ( F (1, 24) = 10.90; p = 0.003).
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Interactive effects of mGlu5 and 5-HT2A receptors on locomotor activity in mice.
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