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Modelling the protective efficacy of alternative delivery schedules for intermittent preventive treatment of malaria in infants and children.

PLoS One · 2011 · PMC3080380 · PMID 21533088

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an overall trendno p-value reported
These studies found an overall trend of decreasing efficacy with increasing SP resistance, but the exact relationship between prevalence of key resistance markers and IPT efficacy is not well characterised.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.