Expression of a dominant negative CELF protein in vivo leads to altered muscle organization, fiber size, and subtype.

Although the decrease in inclusion did not quite reach statistical significance for C10orf97 exon 5 in pectoral muscle, a significant decrease was found in thigh muscles from the same mice (41.4±1.8% in wild type versus 32.5±3.7% inclusion in Myo-CELFΔ-370 mice, P = 0.01).

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