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Tamoxifen in early-stage estrogen receptor-positive breast cancer: overview of clinical use and molecular biomarkers for patient selection.

Onco Targets Ther · 2010 · PMC3084302 · PMID 21552410

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a nonsignificant trendno p-value reported
An initial analysis at 2.75 years showed a nonsignificant trend in disease-free survival benefit, indicating an improved outcome with exemestane versus tamoxifen in the intent to treat population. 32 Excluding patients who have never received a study drug, disease-free survival significantly improved with exemestane.

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