Barely Significant
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Impact of the NICE guideline recommending cessation of antibiotic prophylaxis for prevention of infective endocarditis: before and after study.

BMJ · 2011 · PMC3086390 · PMID 21540258

Europe PMCDOI
2
hedged sentences
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

an increasing trendP<0.001actually significant
From January 2000 to March 2008, there was an increasing trend in the number of cases of infective endocarditis (P<0.001), cases possibly attributable to oral streptococci (P<0.001), and deaths from infective endocarditis (P=0.008).

also in 63,971 other papers

highly significantP<0.001actually significant
Results After the introduction of the NICE guideline there was a highly significant 78.6% reduction (P<0.001) in prescribing of antibiotic prophylaxis, from a mean 10 277 (SD 1068) prescriptions per month to 2292 (SD 176).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.