Barely Significant
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Ancient origin of animal U-box ubiquitin ligases.

BMC Evol Biol · 2010 · PMC3087547 · PMID 20979629

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highly significantno p-value reported
Understanding the groups of proteins that are either involved in ubiquitinating or in regulating the ubiquitination system is therefore highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.