The expression level of VEGF-A mRNA in CSF cells and PBMC was positively correlated in the SPMS group in study group A (R 2 = 0,17, p-value: 0.01612) and with borderline significance in study group B (R 2 = 0,19, p-value 0,059).
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The expression of VEGF-A is down regulated in peripheral blood mononuclear cells of patients with secondary progressive multiple sclerosis.
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