HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention.

Retrovirology · 2011 · PMC3090340 · PMID 21489275

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highly significantno p-value reported

In combination with the aforementioned abilities of Vpr to increase viral replication by inducing G 2 arrest and activating the HIV-1 LTR, the potential of Vpr to promote infection of and survival of macrophages could be a highly significant factor in the development and/or maintenance of macrophage viral reservoirs.

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