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Frequency and predictors of tablet splitting in statin prescriptions: a population-based analysis.

Open Med · 2008 · PMC3091608 · PMID 21602952

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an increasing trendno p-value reported
There was an increasing trend in the practice over time, to 4.5% of prescriptions in 2006.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.