highly significantp <0.001
A highly significant fraction (74%) of all downregulated genes were direct targets of TDP-43 in comparison to genes that were unchanged (52%, p <0.001) or upregulated (18%, p <1×10 −17 ) upon TDP-43 depletion.
A highly significant fraction (74%) of all downregulated genes were direct targets of TDP-43 in comparison to genes that were unchanged (52%, p <0.001) or upregulated (18%, p <1×10 −17 ) upon TDP-43 depletion.