Inferring functional modules of protein families with probabilistic topic models.

BMC Bioinformatics · 2011 · PMC3098182 · PMID 21554720

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highly significantno p-value reported

The average percentage of verified pairwise functional couplings for all 198 modules of the exemplary run is 14.9% (Figure 2 ), and the individual results for the modules are highly significant according to an estimate based on the hypergeometric distribution (Methods).

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