Biochemical characteristics of the parental antigens The bias toward membrane-associated proteins as CTL peptide carriers in subset I, and the highly significant percent of responders within this subset as compared to the randomly selected peptide binders (subset II), prompted us to analyze the hydrophobicity/hydrophilicity character of the individual peptides (see Materials & Methods ).
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Whole-genome immunoinformatic analysis of F. tularensis: predicted CTL epitopes clustered in hotspots are prone to elicit a T-cell response.
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