Clinical outcome of adjuvant endocrine treatment according to Her-2/neu status in breast cancer.

Indian J Med Res · 2011 · PMC3100149 · PMID 21321422

Europe PMC

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may be significantno p-value reported

Both alterations may be significant for ligand-independent ER activation with loss of the inhibitory effect of tamoxifen on ER-mediated transcription, providing a viable mechanism to explain the association of Her-2/neu with tamoxifen resistance 22 .

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