A synthetic HIV-1 subtype C backbone generates comparable PR and RT resistance profiles to a subtype B backbone in a recombinant virus assay.

PLoS One · 2011 · PMC3101197 · PMID 21629677

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highly significantno p-value reported

The increase in FC is most pronounced and highly significant (p = <0.0001) for both 3TC and FTC and for both subtype backbones.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.