A topical microbicide gel formulation of CCR5 antagonist maraviroc prevents HIV-1 vaginal transmission in humanized RAG-hu mice.

PLoS One · 2011 · PMC3105981 · PMID 21673796

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highly significantno p-value reported

Thus protection conferred by maraviroc gel against HIV-1 vaginal challenge is highly significant (p value 0.0006, Fisher's exact test).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.