Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniae.

Mol Cell Proteomics · 2011 · PMC3108842 · PMID 21474794

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

almost reached statistical significancep = 0.058so close (0.05 < p ≤ 0.1)

pneumoniae exposed triplicate only identified two of our five targets (with a third having a p value that almost reached statistical significance p = 0.058, data not shown) but this appeared to reflect the stringency of our statistical approach because all five proteins were differentially regulated by Western blotting.

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