Barely Significant
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Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.

PLoS One · 2011 · PMC3108993 · PMID 21677778

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borderline significantno p-value reported
Paradoxically there is a borderline significant increase in the level of γ1 germline transcripts in the Helios −/− OTII cell chimeras.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.