We demonstrate that this increased expression of Nox4 in tg mice results in a highly significant upregulation in the expression of Nrf2-regulated genes, including those involved in glutathione (GSH) biosynthesis and recycling.
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We demonstrate that this increased expression of Nox4 in tg mice results in a highly significant upregulation in the expression of Nrf2-regulated genes, including those involved in glutathione (GSH) biosynthesis and recycling.