borderline significantP = 0.05
We observed reduced levels (β-coefficient [95% CI]) of HOMA-B for children and adolescents carrying glucose-raising alleles in or near GLIS3 (−0.023 [−0.040 to −0.006], P = 0.007) with borderline significant associations for ADCY5 (−0.019 [0.0002 to −0.038], P = 0.05) and PROX1 (−0.016 [−0.033 to 0.001], P = 0.067).