Again a highly significant loss of IFN-γ-dependent control of parasite proliferation was seen in the K-Irga6 −/− cells compared with the K-C57BL/6 wild-type cells ( Figure 5B ).
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The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.
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