Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated process.

Int J Chron Obstruct Pulmon Dis · 2011 · PMC3119106 · PMID 21697995

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

borderline significantP = 0.08so close (0.05 < p ≤ 0.1)

Twelve weeks of smoke exposure led to a borderline significant increase in CHOP levels ( P = 0.08), observed by Western blot ( Figures 4A and B ).

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a possible trendno p-value reported

Cigarette smoke exposure and CHOP in guinea pig lungs Following our observations of a possible trend towards an increase in CHOP expression in mouse lungs following cigarette smoke, we determined the influence of cigarette smoke on CHOP expression in an additional animal model.

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