Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis.

PLoS Genet · 2011 · PMC3121741 · PMID 21731497

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highly significantno p-value reported

This highly significant motif (MEME E-value = 8.3 −385 ) is in agreement with the known Transfac database IRF8 binding motif (ICSBP_M00699; Figure S1B ), although there is no requirement for the 3′ CTG bases that are more characteristic of the ISGF3 (Stat1/Stat2/IRF9) ISRE binding site ( Figure 3A ).

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