Systemic BCG immunization induces persistent lung mucosal multifunctional CD4 T(EM) cells which expand following virulent mycobacterial challenge.

PLoS One · 2011 · PMC3123368 · PMID 21720558

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highly significantno p-value reported

Upon determination of bacterial load four weeks after challenge, BCG immunised groups displayed highly significant protection in the spleen ∼1.5 log 10 (ρ<0.001) and lungs ∼2 log 10 (ρ<0.01) ( Table 1 A , representative data of 1 of 4 separate experiments).

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