highly significantp < 0.0001
This highly significant increase (ANOVA, p < 0.0001, followed by a Tukey-Kramer HSD) in the total number of niche cells in the absence of an increase in the number of S phase cells, may also suggest that the 1 st -generation neuronal precursor cells in the crayfish niche are not self-renewing because their numbers can increase without additional cell divisions among the niche cells.