HOPS drives vacuole fusion by binding the vacuolar SNARE complex and the Vam7 PX domain via two distinct sites.

Mol Biol Cell · 2011 · PMC3135484 · PMID 21613544

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The sentences

may not be significantno p-value reported

We consider it likely that the fusion defect caused by the additional truncation of Vam3 in the double mutant is underestimated, as differences at this low fusion activity may not be significant.

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