highly significantP =0.001
When cases with either TP53 mutation (L2/L3 type) or GMP+ were combined, there was a highly significant association with disease progression (PD) ( P =0.001).
When cases with either TP53 mutation (L2/L3 type) or GMP+ were combined, there was a highly significant association with disease progression (PD) ( P =0.001).
Logistic regression analysis revealed TP53 mutations (wild type and non-L2/L3 vs L2/L3 mutations) to predict disease progression independently ( P =0.005) ( Aas et al , 1996 ; Geisler et al , 2003 ), whereas GMP status showed an independent association with disease progression of borderline significance ( P =0.07).