Glucose regulates free cytosolic Zn²⁺ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells.

J Biol Chem · 2011 · PMC3138249 · PMID 21613223

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highly significantp < 0.001actually significant

These changes become highly significant (853 ± 96 p m versus 452 ± 42 p m , p < 0.001) after 24 h and are associated with increased expression of the Zn 2+ importer family members Slc39a6 , Slc39a7 , and Slc39a8 , and decreased expression of metallothionein 1 and 2.

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